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A longitudinal study of circulating immune complexes (CIC) of the IgG class has been undertaken in patients presenting for operation of active malignant disease of the female reproductive tract. These values were compared with data obtained during subsequent clinical remission and prior to the clinical diagnosis of relapse. The results showed that irrespective of the site of disease (e.g., ovary, fallopian tube, cervix, endometrium, or vagina) values for CIC were elevated in most patients compared to controls. Postoperative remission status was associated with a significant decrease in values for all tumor sites. Similarly, relapse was associated with elevation of CIC levels to values similar to the preoperative concentrations. It is concluded that CIC may provide a useful biochemical marker of the progression of malignant disease.
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1983,
European journal of gynaecological oncology,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
October 1982,
American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
June 1988,
Gynecologic oncology,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1983,
Immunology letters,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1985,
Cancer detection and prevention,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1993,
Neoplasma,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 2009,
Scandinavian journal of gastroenterology,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
August 1985,
Immunology,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1991,
Advances in experimental medicine and biology,
J K Dodd, and
L J Hicks, and
J P Tyler, and
A J Crandon, and
C N Hudson
January 1986,
Eksperimental'naia onkologiia,
