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We had previously shown that two polypeptides of Plasmodium falciparum are preferentially recognized by antibodies of resistant squirrel monkeys Saimiri sciureus. Free parasites were isolated from synchronized cultures on human erythrocytes initially inoculated with infected Saimiri erythrocytes. Crude extracts were prepared from mature schizont stages and electrophoresed on preparative NaDodSO4/polyacrylamide gels. Two groups of five monkeys were immunized with protein fractions eluted from the 75- and 100-kilodalton regions of the gels. Strong protection against challenge by the homologous strain of P. falciparum was induced in both groups. Analysis of specific anti-malarial antibodies revealed a homogeneous response of all the animals against a few polypeptides of the mature parasite.
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
April 1984,
Clinical and experimental immunology,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
January 2010,
Human vaccines,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
November 1982,
Parasite immunology,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
May 1996,
Parasitology,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
January 1992,
Memorias do Instituto Oswaldo Cruz,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
June 2013,
BMC biology,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
January 1994,
Vaccine,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
January 2010,
Methods in cell biology,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
June 2020,
Antimicrobial agents and chemotherapy,
P Dubois, and
J P Dedet, and
T Fandeur, and
C Roussilhon, and
M Jendoubi, and
S Pauillac, and
O Mercereau-Puijalon, and
L Pereira Da Silva
March 1999,
Annals of tropical medicine and parasitology,
