-transparent.png){kind=logo}
The effect of 3-aminobenzamide in HeLa cells was examined in several aspects. 10(-3) M 3-aminobenzamide inhibited poly(ADP-ribose) polymerase activity to more than 95% in disrupted nuclei of HeLa cells. The mode of inhibition of the enzyme was competitive inhibition with NAD at a Ki value of 2.5 microM 3-aminobenzamide. The combined treatment of HeLa cells with 3-aminobenzamide and ultraviolet radiation revealed the independent induction of SCEs by these 2 agents.
Related Publications
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
January 1984,
Cytogenetics and cell genetics,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
July 1982,
Mutation research,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
January 1984,
Cytogenetics and cell genetics,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
November 1977,
Mutation research,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
May 1985,
Carcinogenesis,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
February 1979,
Mutation research,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
June 1974,
Nature,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
September 1985,
Mutation research,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
December 1986,
Cell biology and toxicology,
F Otsuka, and
H Ohno, and
T Enomoto, and
F Hanaoka, and
M Yamada
October 1984,
Mutation research,
