-transparent.png){kind=logo}
An immunocytochemical study of 30 retinoblastomas was carried out using antibodies to neuronal and glial markers. The tumours were found to react with antibodies to neuron-specific enolase (NSE), a marker for neuronal elements, and S-100 and glial fibrillary acidic protein (GFAP), both of which are proteins present in glia. Two distinct cell populations were found within the tumour: the first, composed of anaplastic tumour cells at various stages of differentiation, showed both NSE and S-100 immunoreactivity; the second cell type, which immuno-stained for S-100 and GFAP, resembled mature glial cells. The results of this study indicate that the retinoblastoma may arise from a pluripotential primitive cell partially retaining neuronal and glial characteristics.
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
January 2016,
Arquivos brasileiros de oftalmologia,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
November 1994,
Current eye research,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
August 1984,
Experimental eye research,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
August 1995,
The British journal of ophthalmology,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
May 1991,
The American journal of pathology,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
June 2007,
Molecular vision,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
January 1984,
Virchows Archiv. A, Pathological anatomy and histopathology,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
August 1988,
Experientia,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
January 1990,
Journal of neurosurgical sciences,
G Terenghi, and
J M Polak, and
J Ballesta, and
D Cocchia, and
F Michetti, and
D Dahl, and
P J Marangos, and
A Garner
June 2008,
Journal of neural transmission (Vienna, Austria : 1996),
