-transparent.png){kind=logo}
The activity of HMG-CoA reductase and cholesterol 7 alpha-hydroxylase was assayed in the liver of rats, rabbits, hamsters and guinea pigs at the minimum of the day cycle and after one night fasting. The amount of HMG-CoA reductase, as determined after its complete dephosphorylation in vitro was of the same order of magnitude in the tested species. The dephosphorylated active form of the enzyme was detectable only in the rat. Cholesterol 7 alpha-hydroxylase activity was also much higher in the rat. Cholestyramine treatment stimulated the activity of both enzymes. In particular, the ratio between active and inactive HMG-CoA reductase in rabbits, hamsters and guinea pigs became of the same order of magnitude of that found in rats.
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
January 1997,
Sub-cellular biochemistry,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
June 1977,
Experimental and molecular pathology,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
February 1988,
Journal of lipid research,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
September 1985,
FEBS letters,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
July 1997,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
January 1987,
Advances in experimental medicine and biology,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
February 1994,
Journal of lipid research,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
July 1994,
Biochemical and biophysical research communications,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
November 1972,
Journal of lipid research,
G Cighetti, and
E Bosisio, and
G Galli, and
M Galli Kienle
December 1990,
Journal of lipid research,
