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The clinical and angiographic findings in 2 patients with focal macular choroidopathy (FMC) are described. Follow-up fluorescein angiography revealed that the initial lesions consisted of multifocal, whitish spot-like areas of choroidal infiltration with hyperfluorescence in the late phase angiogram. At a later stage of the disease, the developing disciform macular lesion showed subretinal neovascularization. The disease was bilateral with poor visual prognosis. There was no evidence of infection with Histoplasma capsulatum. Early oral corticosteroid treatment could not prevent the progressive nature of the disease.
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