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Concanavalin A coupled to the naturally occurring iron storage protein ferritin is used to label rat erythrocytes and increase the cells' magnetic susceptibility. Labeled cells are introduced into a chamber containing spherical iron particles and the chamber is placed in a uniform 5.2 kG (gauss) magnetic field. The trajectory of cells in the inhomogeneous magnetic field around the iron particles and the polar distributions of cells bound to the iron particles compare well with the theoretical predictions for high gradient magnetic systems. On the basis of these findings we suggest that ferritin conjugated ligands can be used for selective magnetic separation of labeled cells.
L L Odette, and
M A McCloskey, and
S H Young
May 1983,
Biophysical journal,
L L Odette, and
M A McCloskey, and
S H Young
January 2013,
Environmental science & technology,
L L Odette, and
M A McCloskey, and
S H Young
October 1963,
Laboratory investigation; a journal of technical methods and pathology,
L L Odette, and
M A McCloskey, and
S H Young
August 2020,
Journal of biomedical materials research. Part B, Applied biomaterials,
L L Odette, and
M A McCloskey, and
S H Young
July 2019,
Mikrochimica acta,
L L Odette, and
M A McCloskey, and
S H Young
January 2007,
Contrast media & molecular imaging,
L L Odette, and
M A McCloskey, and
S H Young
January 1984,
Histochemistry,
L L Odette, and
M A McCloskey, and
S H Young
January 2011,
Methods in molecular biology (Clifton, N.J.),
L L Odette, and
M A McCloskey, and
S H Young
January 2023,
Molecules (Basel, Switzerland),
L L Odette, and
M A McCloskey, and
S H Young
January 2009,
Angewandte Chemie (International ed. in English),
