Biomaterial Database

Discharge of intrapulmonary chemoreceptors and its modulation by rapid F1CO2 changes in decerebrate ducks. 1980

P J Berger, and R D Tallman, and A L Kunz

Single-unit activity was recorded from intrapulmonary chemoreceptors (IPC) in decerebrate ducks inspiring room air (fresh air or control breath), or a short pulse of room air preceded and followed by 5% CO2 (fresh air pulse or experimental breath). Of 36 IPC studied, 28 fired a burst of impulses of similar duration to the fresh air pulse; delaying the fresh air pulse until later and later in inspiration progressively delayed the IPC burst. The remaining 8 IPC did not respond discretely to the fresh air pulse, rather their discharge was reduced diffusely in one or both of the ventilatory phases. The average discharge of the IPC population had a cyclic character during control breathing, with peak discharge mid-way through inspiration and essentially a constant discharge during expiration. An experimental breath had a similar IPC discharge pattern but peak inspiratory discharge was reduced; delaying the fresh air pulse delayed the population IPC burst. The results indicate that IPC could mediate the previously reported changes in T1 and TE that occur when the timing of a fresh air pulse is manipulated in conscious chickens [(Tallman et al. (1979). Am. J. Physiol. 237: R260-R265)].

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D002628	Chemoreceptor Cells	Cells specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptor cells may monitor external stimuli, as in TASTE and OLFACTION, or internal stimuli, such as the concentrations of OXYGEN and CARBON DIOXIDE in the blood.	Chemoreceptive Cells,Cell, Chemoreceptive,Cell, Chemoreceptor,Cells, Chemoreceptive,Cells, Chemoreceptor,Chemoreceptive Cell,Chemoreceptor Cell
D003655	Decerebrate State	A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358)	Decerebrate Posturing,Decorticate Rigidity,Decorticate State,Rigidity, Decerebrate,Rigidity, Decorticate,Decerebrate Posturings,Decerebrate Rigidity,Decerebrate States,Decorticate Rigidities,Decorticate States,Posturing, Decerebrate,Posturings, Decerebrate,Rigidities, Decorticate,State, Decerebrate,States, Decerebrate
D004372	Ducks	A water bird in the order Anseriformes (subfamily Anatinae (true ducks)) with a broad blunt bill, short legs, webbed feet, and a waddling gait.	Duck
D000200	Action Potentials	Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.	Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor