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The effects of dietary sodium molybdate and sodium tungstate on eye color and aldehyde oxidase and xanthine dehydrogenase activities have been determined in Drosophila melanogaster. Dietary sodium tungstate administration has been used as a screening procedure to identify two new lxd alleles. Tungstate administration results in increased frequencies of "brown-eyed" flies in lxd stocks and a coordinate decrease in AO and XDH activities in all genotypes tested. The two new lxd alleles affect AO and XDH in a qualitatively but not quantitatively similar fashion to the original lxd allele. AO and XDH activity and AO-CRM levels appear much more sensitive to mutational perturbations of this gene-enzyme than do XDH-CRM levels in the genotypes tested.
M M Bentley, and
J H Williamson, and
M J Oliver
April 1964,
Genetics,
M M Bentley, and
J H Williamson, and
M J Oliver
October 1976,
Developmental biology,
M M Bentley, and
J H Williamson, and
M J Oliver
February 1982,
Biochemical genetics,
M M Bentley, and
J H Williamson, and
M J Oliver
January 1985,
Experientia,
M M Bentley, and
J H Williamson, and
M J Oliver
January 1981,
Molecular & general genetics : MGG,
M M Bentley, and
J H Williamson, and
M J Oliver
April 1979,
Molecular & general genetics : MGG,
M M Bentley, and
J H Williamson, and
M J Oliver
October 2004,
Chemical research in toxicology,
M M Bentley, and
J H Williamson, and
M J Oliver
February 1975,
Biochemical genetics,
M M Bentley, and
J H Williamson, and
M J Oliver
January 1984,
Comparative biochemistry and physiology. B, Comparative biochemistry,
M M Bentley, and
J H Williamson, and
M J Oliver
January 1978,
Comparative biochemistry and physiology. B, Comparative biochemistry,
