-transparent.png){kind=logo}
The effect of TRH administration to the term pregnant women on the GH response in cord blood (CB) was evaluated in 138 subjects. Previous studies have demonstrated that TRH readily crosses the placenta. TRH (400 microgram) was administered iv to 59 pregnant women just before delivery. CB samples were obtained at delivery and assigned to 6 groups, depending upon the duration of time between TRH injection and CB sampling. The control group comprised 79 pregnant women who received saline. A progressive rise and then a fall in the CB GH concentration were observed after TRH administration. Values were significantly elevated 61-90 min after TRH administration compared to values in saline-treated subjects (19.3 +/- 3.1 vs. 13.1 +/- 0.9 ng/ml; P less than 0.05). The present study is the first report of the effect of TRH on the GH concentration in CB and suggests that TRH stimulates GH release in the fetus.
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
May 1981,
The Journal of clinical endocrinology and metabolism,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
August 1984,
Endocrinologia japonica,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
August 1980,
Endocrinologia japonica,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
May 1991,
American journal of obstetrics and gynecology,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
January 1978,
Biology of the neonate,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
January 1980,
Neuropsychobiology,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
August 1985,
Zhonghua yi xue za zhi,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
September 1990,
Journal of endocrinological investigation,
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
January 1984,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
E Roti, and
A Gnudi, and
G Robuschi, and
R Emanuele, and
L Benassi, and
L E Braverman
February 1973,
Endocrinology,
