Biomaterial Database

The dependence of the Chou-Fasman parameters on amino acid side chain structure. 1983

M Charton, and B I Charton

The Chou-Fasman conformational parameters, P, for amino acid residues in proteins are shown to be a linear function of intermolecular force and steric parameters. For alpha- helix, coil and turn parameters, steric effects are predominant; whereas for beta-sheet parameters, intramolecular forces are predominant. Turn and coil parameters show little or no difference in their dependence which is different from that of alpha-helix and in some ways almost reciprocal. Factors which increase the probability of finding an amino acid residue in an alpha-helix usually decrease the probability of finding it in coil or turn. Values of P were calculated for several of the less common amino acids.

UI	MeSH Term	Description	Entries
D008956	Models, Chemical	Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.	Chemical Models,Chemical Model,Model, Chemical
D011336	Probability	The study of chance processes or the relative frequency characterizing a chance process.	Probabilities
D011487	Protein Conformation	The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).	Conformation, Protein,Conformations, Protein,Protein Conformations
D000596	Amino Acids	Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.	Amino Acid,Acid, Amino,Acids, Amino