Biomaterial Database

[Use of hexetidine as an oral cavity antiseptic]. 1980

P Menghini, and P L Sapelli

Of the many products recommended for topical use in the prevention and control of odontostomatological diseases, those containing hexetidine have proved to combine detergent properties with a true, specific activity. Reference is made to the abundant literature in an account of the composition, antibacterial spectrum, pharmacokinetics, mechanism and action time of this molecule. The conclusion is reached that, with proper support in the form of general drug management, hexetidine is effective in the treatment of odontostomatological and ORL sepsis.

UI	MeSH Term	Description	Entries
D009910	Oral Hygiene	The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.	Dental Hygiene,Hygiene, Dental,Hygiene, Oral
D003773	Dental Plaque	A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.	Plaque, Dental
D005891	Gingivitis	Inflammation of gum tissue (GINGIVA) without loss of connective tissue.	Gingivitides
D006590	Hexetidine	A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)	Bactidol,Doreperol,Duranil,Elsix,Hexigel,Hexoral,Hextril,Oraldene,Oraldine,Steri-sol
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000891	Anti-Infective Agents, Local	Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.	Anti-Infective Agents, Topical,Antiseptic,Antiseptics,Microbicides, Local,Microbicides, Topical,Antiinfective Agents, Local,Antiinfective Agents, Topical,Local Anti-Infective Agents,Local Antiinfective Agents,Topical Anti-Infective Agents,Topical Antiinfective Agents,Agents, Local Anti-Infective,Agents, Local Antiinfective,Agents, Topical Anti-Infective,Agents, Topical Antiinfective,Anti Infective Agents, Local,Anti Infective Agents, Topical,Local Anti Infective Agents,Local Microbicides,Topical Anti Infective Agents,Topical Microbicides
D013329	Structure-Activity Relationship	The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.	Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships