-transparent.png){kind=logo}
V3703 (Stomadhex) is a tablet with bioadhesive properties enabling it to remain in place for several hours after it has been placed on the oral mucosa. It continuously releases chlorhexidine and niacinamide. In a study conducted in 15 dogs, the tablets were well tolerated by the animals. The product significantly reduced (p < 0.05): dental plaque; quantitative periodontopathogen and total anaerobic bacterial counts; spirochetes; and halitosis when used daily over a 14 day period. Gingivitis was also reduced, though not significantly (p = 0.07). Stomadhex treatment can provide a carry-over effect following dental scaling by reducing oral microflora and retarding the reappearance of dental plaque.
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
February 2001,
Drug development and industrial pharmacy,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
June 2003,
Bollettino chimico farmaceutico,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
September 2003,
Bollettino chimico farmaceutico,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
August 1996,
Pharmaceutical research,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
January 1980,
Minerva stomatologica,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
January 2002,
Medicinski arhiv,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
August 2004,
Pharmaceutical development and technology,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
January 1998,
Journal of dental research,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
January 1992,
European journal of clinical pharmacology,
P Gruet, and
C Gaillard, and
B Boisramé, and
D Duffaut, and
A M Grimoud, and
G Camy
January 2009,
AAPS PharmSciTech,
