Thallium-201 myocardial scintigraphy: a critical comparison of seven-pinhole tomography and conventional planar imaging. 1981

H R Rizi, and R C Kline, and J H Thrall, and M C Besozzi, and J W Keyes, and W L Rogers, and J Clare, and B Pitt

Seven-pinhole tomographic and planar thallium-201 imaging was performed on 63 consecutive patients to assess the clinical value of these techniques. Significant coronary artery disease (stenosis greater than or equal to 70%) was present in 52 patients. Comparing the seven-pinhole results with those of the planar, the findings for sensitivity, specificity, and inter- and intraobserver agreement were, respectively, 94% against 75% (p less than 0.005), 91% against 91%, 86% against 79%, and 97% against 92%. In 25 patients in this group with a prior myocardial infarction, sensitivity was 100% for tomographic imaging and 92% for planar. In 27 patients without prior myocardial infarction, by contrast, sensitivity for tomographic imaging was 89% and for planar imaging 59% (p less than 0.01). Thus we conclude that both tomographic and planar imaging are highly sensitive for the detection of significant coronary artery disease, but tomographic imaging is significantly more sensitive in patients without prior myocardial infarction.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D011868 Radioisotopes Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Daughter Isotope,Daughter Nuclide,Radioactive Isotope,Radioactive Isotopes,Radiogenic Isotope,Radioisotope,Radionuclide,Radionuclides,Daughter Nuclides,Daugter Isotopes,Radiogenic Isotopes,Isotope, Daughter,Isotope, Radioactive,Isotope, Radiogenic,Isotopes, Daugter,Isotopes, Radioactive,Isotopes, Radiogenic,Nuclide, Daughter,Nuclides, Daughter
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D005082 Physical Exertion Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included. Physical Effort,Effort, Physical,Efforts, Physical,Exertion, Physical,Exertions, Physical,Physical Efforts,Physical Exertions
D005188 False Negative Reactions Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed) False Negative Reaction,Reaction, False Negative,Reactions, False Negative
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013793 Thallium A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl. Thallium-205,Thallium 205

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