A glucose-controlled insulin infusion system for diabetic women during labour. 1978

M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle

A glucose-controlled insulin infusion system was used to control blood glucose concentration during labour or caesarean section in six insulin-dependent diabetics. The mean blood glucose concentration during the four hours of labour immediately before delivery was 4.6-5.2 mmol/1 (82.9-93.7 mg/100 ml). Feedback control of insulin delivery by blood glucose concentration should decrease the risk of postpartum hypoglycaemia in the infant and allow normal obstetric management for the insulin-dependent diabetic in labour.

UI MeSH Term Description Entries
D007003 Hypoglycemia A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. Fasting Hypoglycemia,Postabsorptive Hypoglycemia,Postprandial Hypoglycemia,Reactive Hypoglycemia,Hypoglycemia, Fasting,Hypoglycemia, Postabsorptive,Hypoglycemia, Postprandial,Hypoglycemia, Reactive
D007263 Infusions, Parenteral The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping. Intra-Abdominal Infusions,Intraperitoneal Infusions,Parenteral Infusions,Peritoneal Infusions,Infusion, Intra-Abdominal,Infusion, Intraperitoneal,Infusion, Parenteral,Infusion, Peritoneal,Infusions, Intra-Abdominal,Infusions, Intraperitoneal,Infusions, Peritoneal,Intra Abdominal Infusions,Intra-Abdominal Infusion,Intraperitoneal Infusion,Parenteral Infusion,Peritoneal Infusion
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D007743 Labor, Obstetric The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED). Obstetric Labor
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011254 Pregnancy in Diabetics The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy. Pregnancy in Diabetes,Pregnancy in Diabete,Pregnancy in Diabetic
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D002585 Cesarean Section Extraction of the FETUS by means of abdominal HYSTEROTOMY. Abdominal Delivery,Delivery, Abdominal,C-Section (OB),Caesarean Section,Postcesarean Section,Abdominal Deliveries,C Section (OB),C-Sections (OB),Caesarean Sections,Cesarean Sections,Deliveries, Abdominal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
May 1977, British medical journal,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
December 2012, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
March 1981, Diabete & metabolisme,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
June 1979, Medical progress through technology,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
July 1984, Acta endocrinologica,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
August 1978, Clinical chemistry,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
January 1979, Hormone and metabolic research. Supplement series,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
August 1981, Diabetologia,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
January 1977, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
M Nattrass, and K G Alberti, and K J Dennis, and P N Gillibrand, and A T Letchworth, and A L Buckle
March 1982, Canadian Medical Association journal,
Copied contents to your clipboard!