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The antiarrhythmic effect of metoprolol after chronic treatment has been evaluated by 24 hour Holter monitoring in 16 patients with several premature ventricular beats and in 14 patients with chronic atrial fibrillation and compared with the effect of a placebo. Metoprolol induced a mean decrease of heart rate of 14.5% in the 16 patients and reduced the mean value/min of the ventricular premature beats of the 51.2%. In addition the use of metoprolol abolished the ventricular premature beats in 9 cases, while in two cases there was an increase of their frequency. In the 14 patients with chronic atrial fibrillation metoprolol was able to reverse to sinus rhythm three of the patients and in the remaining 11 decreased the ventricular heart rate of the 33%.
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
November 1978,
Klinische Monatsblatter fur Augenheilkunde,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
December 1979,
Yao xue xue bao = Acta pharmaceutica Sinica,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
January 1980,
Giornale italiano di cardiologia,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
January 1976,
Giornale italiano di cardiologia,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
February 1981,
Medicina clinica,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
September 1981,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
May 1977,
Kokyu to junkan. Respiration & circulation,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
January 1979,
Zhonghua xin xue guan bing za zhi,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
April 1974,
Kokyu to junkan. Respiration & circulation,
R Bolognesi, and
G Bruno, and
G Burani, and
L Codecá, and
F N Effendy, and
P Gruppillo
September 1980,
Klinische Wochenschrift,
