Biomaterial Database

[Virologic diagnosis of rubella. Findings in a rubella epidemic in a military training camp]. 1980

F Burkhardt, and U Schilt, and H Saner

During a minor rubella epidemic in a Swiss army recruit training camp (Spring 1978), recent rubella infection was proved in 20 out of 22 investigated cases. In 18 cases virus replication could be shown by means of indirect immunofluorescence (IIF). Due to its higher sensitivity and easier performance in comparison with conventional echo interference, we believe IIF should be the method of choice for rubella virus isolation. In 2 out of 22 cases, the possibility of a secondary infection was discussed. A chceklist is given showing the necessary steps for virological investigations we think should be carried out to define immunity status, confirm or rule out a rubella infection, particular weight being attached to the embryopathy question. This article is therefore intended to provide the clinician interested in virological problems with a total to enable him to take the necessary measures for detection of rubella infection and interpretation of laboratory findings.

UI	MeSH Term	Description	Entries
D007075	Immunoglobulin M	A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin.	Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D008297	Male		Males
D008887	Military Medicine	The practice of medicine as applied to special circumstances associated with military operations.	Medicine, Military
D005455	Fluorescent Antibody Technique	Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.	Antinuclear Antibody Test, Fluorescent,Coon's Technique,Fluorescent Antinuclear Antibody Test,Fluorescent Protein Tracing,Immunofluorescence Technique,Coon's Technic,Fluorescent Antibody Technic,Immunofluorescence,Immunofluorescence Technic,Antibody Technic, Fluorescent,Antibody Technics, Fluorescent,Antibody Technique, Fluorescent,Antibody Techniques, Fluorescent,Coon Technic,Coon Technique,Coons Technic,Coons Technique,Fluorescent Antibody Technics,Fluorescent Antibody Techniques,Fluorescent Protein Tracings,Immunofluorescence Technics,Immunofluorescence Techniques,Protein Tracing, Fluorescent,Protein Tracings, Fluorescent,Technic, Coon's,Technic, Fluorescent Antibody,Technic, Immunofluorescence,Technics, Fluorescent Antibody,Technics, Immunofluorescence,Technique, Coon's,Technique, Fluorescent Antibody,Technique, Immunofluorescence,Techniques, Fluorescent Antibody,Techniques, Immunofluorescence,Tracing, Fluorescent Protein,Tracings, Fluorescent Protein
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000914	Antibodies, Viral	Immunoglobulins produced in response to VIRAL ANTIGENS.	Viral Antibodies
D012409	Rubella	An acute infectious disease caused by the RUBELLA VIRUS. The virus enters the respiratory tract via airborne droplet and spreads to the LYMPHATIC SYSTEM.	Measles, German,Three Day Measles,German Measles,Measle, Three Day,Measles, Three Day,Rubellas,Three Day Measle
D012412	Rubella virus	The type (and only) species of RUBIVIRUS causing acute infection in humans, primarily children and young adults. Humans are the only natural host. A live, attenuated vaccine is available for prophylaxis.	Measles Virus, German,German Measles Virus