-transparent.png){kind=logo}
The effect of a pineal polypeptide extract was tested against the effect of melatonin on the serum level and pituitary concentration of LH and FSH of the adult male rat both in basal conditions and in response to exogenous (GnRH) and endogenous (castration) stimulation. A 2 ml dose of pineal polypeptides per injection caused a signifcant fall in serum LH and FSH both in the intact, the intact + GnRH, and the castrated animals. The decrease in pituitary concentration of LH and FSH was of statistical significance only in stimulation conditions. A 50 micrograms dose of melatonn/injection failed to produce comparable effects. The antigondaotropic action of the biologically active pineal compounds is discussed.
E Damian, and
O Ianăş, and
I Bădescu
January 1969,
Neuroendocrinology,
E Damian, and
O Ianăş, and
I Bădescu
June 2006,
Journal of endocrinological investigation,
E Damian, and
O Ianăş, and
I Bădescu
June 1974,
Endocrinologia japonica,
E Damian, and
O Ianăş, and
I Bădescu
August 1987,
Acta endocrinologica,
E Damian, and
O Ianăş, and
I Bădescu
October 1970,
Endocrinology,
E Damian, and
O Ianăş, and
I Bădescu
March 1975,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
E Damian, and
O Ianăş, and
I Bădescu
July 1970,
The Journal of clinical endocrinology and metabolism,
E Damian, and
O Ianăş, and
I Bădescu
November 1978,
Radiation research,
E Damian, and
O Ianăş, and
I Bădescu
September 1976,
Nihon Naibunpi Gakkai zasshi,
E Damian, and
O Ianăş, and
I Bădescu
June 1973,
Life sciences. Pt. 2: Biochemistry, general and molecular biology,
