Biomaterial Database

Proximal tubular function in human hydronephrotic kidneys. 1981

C G Bratt, and M Aurell, and G Lindstedt

Proximal tubular was evaluated on the basis of the excretion rate of urinary beta-2-microglobulin of each kidney in 15 patients with unilateral hydronephrosis. Total and divided renal function was measured with 51chromium ethylenediaminetetraacetic acid clearance, isotope renography and a concentration test. Total renal function was normal in all patients. Parenchymal function, measured by renography, was reduced in 2 hydronephrotic kidneys and both patients had had upper urinary tract infections. The ability to concentrate urine was impaired in 10 hydronephrotic kidneys. These patients had renal calculi or had had upper urinary tract infections. The urinary beta-2-microglobulin excretion was normal in all hydronephrotic kidneys, indicating an intact proximal tubular function in these patients.

UI	MeSH Term	Description	Entries
D007671	Kidney Concentrating Ability	The ability of the kidney to excrete in the urine high concentrations of solutes from the blood plasma.	Urine Concentrating Ability,Abilities, Kidney Concentrating,Abilities, Urine Concentrating,Ability, Kidney Concentrating,Ability, Urine Concentrating,Concentrating Abilities, Kidney,Concentrating Abilities, Urine,Concentrating Ability, Kidney,Concentrating Ability, Urine,Kidney Concentrating Abilities,Urine Concentrating Abilities
D007682	Kidney Pelvis	The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.	Renal Pelvis,Pelvis, Kidney,Pelvis, Renal
D007687	Kidney Tubules, Proximal	The renal tubule portion that extends from the BOWMAN CAPSULE in the KIDNEY CORTEX into the KIDNEY MEDULLA. The proximal tubule consists of a convoluted proximal segment in the cortex, and a distal straight segment descending into the medulla where it forms the U-shaped LOOP OF HENLE.	Proximal Kidney Tubule,Proximal Renal Tubule,Kidney Tubule, Proximal,Proximal Kidney Tubules,Proximal Renal Tubules,Renal Tubule, Proximal,Renal Tubules, Proximal,Tubule, Proximal Kidney,Tubule, Proximal Renal,Tubules, Proximal Kidney,Tubules, Proximal Renal
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006869	Hydronephrosis	Abnormal enlargement or swelling of a KIDNEY due to dilation of the KIDNEY CALICES and the KIDNEY PELVIS. It is often associated with obstruction of the URETER or chronic kidney diseases that prevents normal drainage of urine into the URINARY BLADDER.	Hydronephroses
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths