-transparent.png){kind=logo}
Seventy-one patients with mild-to-moderate essential hypertension completed 14 weeks' treatment with a single daily dose of fixed combination of metoprolol tartrate 100 mg and chlorthalidone 25 mg (Logroton; Geigy). This represents 6958 patient-days of treatment. Mean blood pressures, both supine and standing, and pulse rates were reduced to and maintained at clinically acceptable levels during the trial period. No patient prematurely discontinued treatment because of insufficient therapeutic effect. Two patients discontinued the medication for drug-related reasons. Patient compliance was excellent and the preparation was well tolerated. The preparation was judged to be therapeutically effective in more than 80% of cases and is a valuable formulation for antihypertensive therapy.
U Govind, and
B F Munro, and
L I Robertson
January 1980,
Giornale italiano di cardiologia,
U Govind, and
B F Munro, and
L I Robertson
October 1982,
The Medical journal of Australia,
U Govind, and
B F Munro, and
L I Robertson
October 1986,
Minerva cardioangiologica,
U Govind, and
B F Munro, and
L I Robertson
January 2012,
Vascular health and risk management,
U Govind, and
B F Munro, and
L I Robertson
March 1986,
The British journal of clinical practice,
U Govind, and
B F Munro, and
L I Robertson
January 1982,
The Journal of international medical research,
U Govind, and
B F Munro, and
L I Robertson
January 1983,
International journal of clinical pharmacology research,
U Govind, and
B F Munro, and
L I Robertson
January 1979,
Clinical pharmacology and therapeutics,
U Govind, and
B F Munro, and
L I Robertson
April 1996,
Vnitrni lekarstvi,
U Govind, and
B F Munro, and
L I Robertson
February 2022,
Advances in therapy,
