Biomaterial Database

Effect of copper on tissue acid and alkaline phosphates in the green snakehead, Ophiocephalus punctatus (Bloch). 1982

D K Srivastava, and K C Pandey

In vitro exposure to 10(-6) and 10(-5) M copper caused a decline in the activity of acid and alkaline phosphatases in both liver and kidney of Ophiocephalus punctatus. While in vivo exposure to 5 and 7.5 mg/l copper resulted in the activation of alkaline phosphatase in the kidney, the activity of this enzyme in the liver was inhibited at the highest concentration. The acid phosphatase was inhibited in the liver and kidney on in vivo exposure to both concentrations. The varied responses of these enzymes to in vitro and in vivo exposure to copper indicate the involvement of different molecular processes.

UI	MeSH Term	Description	Entries
D007668	Kidney	Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.	Kidneys
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D003300	Copper	A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.	Copper-63,Copper 63
D005399	Fishes	A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D000135	Acid Phosphatase	An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.	Acid beta-Glycerophosphatase,Acid beta Glycerophosphatase
D000469	Alkaline Phosphatase	An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia