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Primary hyperparathyroidism and stone formation in medullary sponge kidneys. 1978

O L Tiktinsky, and V V Nekachalov

The etiological role of primary hyperparathyroidism in stone formation in medullary sponge kidney was studied. The necessity of carrying out special biochemical tests for primary hyperparathyroidism has been shown. The combination of two diseases in cases of stones and nephrocalcinosis is explained by the genetic nature of sponge kidney and primary hyperparathyroidism. 4 patients have been under observation; all underwent successful parathyroidectomy.

UI MeSH Term Description Entries
D006961 Hyperparathyroidism A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
D007669 Kidney Calculi Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE. Kidney Stones,Renal Calculi,Nephrolith,Renal Calculus,Calculi, Kidney,Calculi, Renal,Calculus, Kidney,Calculus, Renal,Kidney Calculus,Kidney Stone,Stone, Kidney,Stones, Kidney
D007691 Medullary Sponge Kidney A non-hereditary KIDNEY disorder characterized by the abnormally dilated (ECTASIA) medullary and inner papillary portions of the collecting ducts. These collecting ducts usually contain CYSTS or DIVERTICULA filled with jelly-like material or small calculi (KIDNEY STONES) leading to infections or obstruction. It should be distinguished from congenital or hereditary POLYCYSTIC KIDNEY DISEASES. Cacchi Ricci Disease,Cacchi-Ricci Syndrome,Kidney, Sponge,Precalyceal Canalicular Ectasia,Cacchi Ricci Syndrome,Canalicular Ectasia, Precalyceal,Canalicular Ectasias, Precalyceal,Disease, Cacchi Ricci,Ectasia, Precalyceal Canalicular,Ectasias, Precalyceal Canalicular,Kidneys, Sponge,Medullary Sponge Kidneys,Precalyceal Canalicular Ectasias,Ricci Disease, Cacchi,Sponge Kidney,Sponge Kidney, Medullary,Sponge Kidneys,Sponge Kidneys, Medullary,Syndrome, Cacchi-Ricci
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014567 Urography Radiography of any part of the URINARY TRACT. Pyelography,Pyelogram,Urogram,Pyelograms,Pyelographies,Urograms,Urographies

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