-transparent.png){kind=logo}
The hamster cell line BHK268-C31 contains two large viral inserts which both include sequences from the left-hand end of adenovirus type 5 (Ad5) DNA. One of these viral inserts has been cloned in the lambda vector Charon 4A. Electron microscopic analysis and restriction enzyme mapping shows that the recombinant carries a 4.4-kb-long colinear segment of viral DNA, which is located between map positions 1.5 and 14.2 in the Ad5 genome. The junctions between viral DNA and flanking sequences have been sequenced and found not to show any specific features. One of the junctions is located in the E1a coding region, 573 bp from the left-hand end of the Ad5 genome, whereas the other junction is situated in the coding region for polypeptide IVa2. The promoter region as well as the cap site for the mRNAs from region E1a are thus missing from this insert and its role in viral transformation is unclear.
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
April 1982,
Journal of virology,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
April 1981,
Journal of molecular biology,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
January 1983,
The EMBO journal,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
March 1982,
Journal of virology,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
January 1977,
Cell,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
September 1978,
Journal of virology,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
December 1982,
Nucleic acids research,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
April 1982,
Nucleic acids research,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
January 1975,
Cold Spring Harbor symposia on quantitative biology,
G Westin, and
L Visser, and
J Zabielski, and
A D van Mansfeld, and
U Pettersson, and
T H Rozijn
July 1977,
The Journal of general virology,
