-transparent.png){kind=logo}
Pharmacokinetics studies were conducted in 4 patients who received buflomedil 100 mg intravenously and in 3 volunteers who received buflomedil 450 mg per os. Buflomedil concentrations were determined by a gas liquid chromatography method. Buflomedil levels declined multiphasically with a mean clearance after intravenous administration of -0,034 (1 h-1 kg-1). The decline appeared to be monophasic after oral administration. In both cases the overall half-life is short, mean 2.07 hrs (range, 1,47-2,6 hrs).
Related Publications
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
January 1981,
European journal of clinical pharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
December 1984,
International journal of clinical pharmacology, therapy, and toxicology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
March 1989,
British journal of clinical pharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
September 1983,
The Journal of antimicrobial chemotherapy,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
November 1982,
International journal of clinical pharmacology, therapy, and toxicology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
January 1983,
European journal of clinical pharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
January 1983,
Cancer chemotherapy and pharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
March 1981,
European journal of clinical pharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
August 1995,
Journal of clinical psychopharmacology,
E Rey, and
G Barrier, and
P d'Athis, and
D de Lauture, and
M O Richard, and
J P Lirzin, and
C Sureau, and
G Olive
January 1983,
Clinical pharmacokinetics,
