Ability of healthy men to discriminate between added inspiratory resistive and elastic loads. 1981

F W Zechman, and R L Wiley, and P W Davenport

Previous studies of the latencies for the detection of inspiratory resistive (R) and elastic (E) loads revealed that R loads were detected earlier in the loaded breath than E loads (Respir. Physiol. 34: 267--77, 1978). These results suggested that the load information generated by R and E loads have different temporal patterns. We hypothesized that these differences might provide a mechanism for subjects to accurately discriminate between R and E loads and secondly, that the R and E load sensations perceived by subjects should have different temporal characteristics. To test these hypotheses we studied six healthy subjects in a two-part study. In this first, two levels of R and E loads (near threshold and 4--5 times threshold) were randomly presented for single inspirations separated by 3--6 unloaded breaths for a total of 10 presentations each. Subjects indicated detection and type of load perceived by pressing R or E marker buttons. In the second part, using the same loading protocol, subjects squeezed a hand grip dynamometer to express the pattern of perceived load sensation. Results indicate that subjects cannot discriminate between near-threshold R and E load but can discriminate between R and E loads 4--5 times threshold with considerable accuracy. Mean grip responses show that perceived load sensations arise earlier and reach maximum values sooner during R loaded breaths. Grip responses are consistent with the previously reported differences in R and E detection latencies and support the hypothesis that load discrimination is mediated by differences in the temporal pattern of load information generated during R and E loaded breaths.

UI MeSH Term Description Entries
D008170 Lung Compliance The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562) Compliance, Lung,Compliances, Lung,Lung Compliances
D008297 Male Males
D012119 Respiration The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration ( Breathing
D012129 Respiratory Function Tests Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc. Lung Function Tests,Pulmonary Function Tests,Function Test, Pulmonary,Function Tests, Pulmonary,Pulmonary Function Test,Test, Pulmonary Function,Tests, Pulmonary Function,Function Test, Lung,Function Test, Respiratory,Function Tests, Lung,Function Tests, Respiratory,Lung Function Test,Respiratory Function Test,Test, Lung Function,Test, Respiratory Function,Tests, Lung Function,Tests, Respiratory Function
D004192 Discrimination, Psychological Differential response to different stimuli. Discrimination, Psychology,Psychological Discrimination
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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