An evaluation of the automated OLLI CD discrete analyser. 1981

G A Harff, and C van Leeuwen

We report the evaluation of a novel clinical chemical analyser, the OLLI CD, which is highly automated compared to its predecessor, the OLLI 3000 analyser. The precision of the dispensing unit, the OLLI D, was assessed with the aid of aqueous solutions of 131I. Sample pipetting of 10 microliter resulted in a coefficient of variation of 0.81%. Lower volumes were unreliable. However, precision of the addition of start reagent for kinetic methods appeared to be only 2.7% for 20 microliter, 1.7% for 50 microliter and 2.1% for 250 microliter. The linearity of response and the precision of the photometer unit, the OLLI C, was assessed with cobalt(II)sulfate solutions. The linearity ranged up to an absorbance of 2.5. The reproducibility of the colorimeter ranged from A510nm 0.0011 to 0.0047. With this analyser good correlations were obtained for alanine aminotransferase (EC 2.6.1.2) vs LKB 8600 reaction rate analyser; for creatinine vs Mark II Autoanalyzer; and for total protein vs SMA 6/60 Autoanalyzer. These three determinations showed acceptable between-day variations. General instrument performance was acceptable.

UI MeSH Term Description Entries
D010783 Photometry Measurement of the various properties of light. Photometries
D011786 Quality Control A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed) Control, Quality,Controls, Quality,Quality Controls
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D003035 Cobalt A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. Cobalt-59,Cobalt 59
D003404 Creatinine Creatinine Sulfate Salt,Krebiozen,Salt, Creatinine Sulfate,Sulfate Salt, Creatinine
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000410 Alanine Transaminase An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2. Alanine Aminotransferase,Glutamic-Pyruvic Transaminase,SGPT,Alanine-2-Oxoglutarate Aminotransferase,Glutamic-Alanine Transaminase,Alanine 2 Oxoglutarate Aminotransferase,Aminotransferase, Alanine,Aminotransferase, Alanine-2-Oxoglutarate,Glutamic Alanine Transaminase,Glutamic Pyruvic Transaminase,Transaminase, Alanine,Transaminase, Glutamic-Alanine,Transaminase, Glutamic-Pyruvic
D001322 Autoanalysis Method of analyzing chemicals using automation. Autoanalyses

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