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Myasthenic reaction with partial neuromuscular block in the electromyogram and increased antibodies against acetylcholine-receptor protein developed during chloroquine administration over two months in a 52-year-old man known for eight years ot have rheumatoid arthritis. When the drug was discontinued and pyridostigmine administration begun, myasthenia improved within six weeks and had completely disappeared after three months. During the same period abnormal neuromuscular transmission regressed. Also, the significantly increased antibodies against acetylcholine-receptor protein became normal. It remains undecided whether this was a drug-induced myasthenia gravis or only a latent myasthenia manifested by the drug.
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
February 1978,
Klinische Wochenschrift,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
September 1981,
Casopis lekaru ceskych,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
December 1979,
Deutsche medizinische Wochenschrift (1946),
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
March 1975,
Zeitschrift fur Erkrankungen der Atmungsorgane,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
December 1977,
Klinische Monatsblatter fur Augenheilkunde,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
February 1981,
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
February 1988,
Muscle & nerve,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
October 1981,
Annales de chirurgie,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
September 1977,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
F Schumm, and
H Wiethölter, and
A Fateh-Moghadam
April 1982,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
