Biomaterial Database

The major histocompatibility complex in the turkey: do erythrocytes bear serologically detectable H antigens? 1980

D K Palmer, and A W Nordskog

An attempt was made to identify erythrocyte cell surface antigens associated with the major histocompatibility complex in the turkey. Two turkey lines, A and B, from the University of Minnesota, putatively homozygous for different major histocompatibility complex alleles, were used for this study. A total of 79 birds were immunized either by skin grafting or by injection of homogenized skin preparation in Freund's incomplete adjuvant. Antisera produced with skin grafts and homogenized skin inoculated intramuscularly both contained red cell agglutinins of low titer. Because agglutination reactions were weak, no sera were suitable for use as line-specific typing fluids. Thus, we were unable to demonstrate that turkey erythrocytes contain serologically detectable major histocompatibility antigens corresponding to the B major histocompatibility system in the chicken or the H-2 system in mice. Rather, the turkey major histocompatibility complex is more like that in rabbits, dogs, monkeys and humans.

UI	MeSH Term	Description	Entries
D004912	Erythrocytes	Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.	Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006649	Histocompatibility Antigens	A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection.	Transplantation Antigens,Antigens, Transplantation,Histocompatibility Antigen,LD Antigens,SD Antigens,Antigen, Histocompatibility,Antigens, Histocompatibility,Antigens, LD,Antigens, SD
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014422	Turkeys	Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae.	Meleagridinae,Meleagrididae