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[The dynamics of the drug release from dragées. Part 3: Indometnacin (author's transl)]. 1980

H Wojdak, and J Pasich

The release of indomethacin from dragées has been determined by the following procedures: flow-through chamber method, stationary basket method, and rotating basket method. The maximum of release was reached within 4 hours. The data obtained with the flow-through chamber and the stationary basket method were similar, whereas those yielded by the rotating basket method were somewhat higher. Furthermore, the release rate constant and the half-life period were calculated.

UI MeSH Term Description Entries
D007213 Indomethacin A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES. Amuno,Indocid,Indocin,Indomet 140,Indometacin,Indomethacin Hydrochloride,Metindol,Osmosin
D002626 Chemistry, Pharmaceutical Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use. Medicinal Chemistry,Chemistry, Pharmaceutic,Pharmaceutic Chemistry,Pharmaceutical Chemistry,Chemistry, Medicinal
D013607 Tablets Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed) Tablet
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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