BIOMAT Database Logo BIOMAT Database Logo

Localization of human A, B and H isoantigens in Cynomolgus monkey tissues. 1980

R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn

The presence and distribution of human A, B and H isoantigens were demonstrated in Cynomolgus monkey (Macaca fascicularis) by means of red cell adherence test. Although no human antigens were found on primate erythrocytes, various epithelial tissues revealed the presence of A, B or H antigenic substance. The distribution and localization was similar to that found in human tissues. Majority of specimens from each individual animal possessed only 1 human type isoantigen with the exception of the salivary and sweat glands, where all animals showed the presence of H antigen in addition to other specificity, and of Brunner's gland, where all sections reacted positively also for A antigen.

UI MeSH Term Description Entries
D007104 Immune Adherence Reaction A method for the detection of very small quantities of antibody in which the antigen-antibody-complement complex adheres to indicator cells, usually primate erythrocytes or nonprimate blood platelets. The reaction is dependent on the number of bound C3 molecules on the C3b receptor sites of the indicator cell. Adherence Reaction, Immune,Adherence Reactions, Immune,Immune Adherence Reactions,Reaction, Immune Adherence,Reactions, Immune Adherence
D007519 Isoantigens Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS. Alloantigens,Alloantigen,Isoantigen
D008251 Macaca A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes. Ape, Barbary,Ape, Black,Ape, Celebes,Barbary Ape,Black Ape,Celebes Ape,Macaque,Apes, Barbary,Apes, Black,Apes, Celebes,Barbary Apes,Black Apes,Celebes Apes,Macacas,Macaques
D008252 Macaca fascicularis A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula. Burmese Long-Tailed Macaque,Crab-Eating Monkey,Cynomolgus Monkey,M. f. aurea,M. fascicularis,Macaca fascicularis aurea,Monkey, Crab-Eating,Monkey, Cynomolgus,Crab-Eating Macaque,Burmese Long Tailed Macaque,Crab Eating Macaque,Crab Eating Monkey,Crab-Eating Macaques,Crab-Eating Monkeys,Cynomolgus Monkeys,Long-Tailed Macaque, Burmese,Macaque, Burmese Long-Tailed,Macaque, Crab-Eating,Monkey, Crab Eating
D004848 Epithelium The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body. Mesothelium,Epithelial Tissue,Mesothelial Tissue,Epithelial Tissues,Mesothelial Tissues,Tissue, Epithelial,Tissue, Mesothelial,Tissues, Epithelial,Tissues, Mesothelial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013045 Species Specificity The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species. Species Specificities,Specificities, Species,Specificity, Species
D014018 Tissue Distribution Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios. Distribution, Tissue,Distributions, Tissue,Tissue Distributions

Related Publications

R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Monoclonal antibody localization of A and B isoantigens in normal and malignant fixed human tissues.
December 1984, The American journal of pathology,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
A, B, and H isoantigens in the human fetus.
October 1973, Developmental biology,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Localization of BRCA1 gene expression in adult cynomolgus monkey tissues.
September 1997, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
A, B & H isoantigens in cervical lesions.
January 1998, Indian journal of pathology & microbiology,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
IL-6R distribution in normal human and cynomolgus monkey tissues.
February 2009, Regulatory toxicology and pharmacology : RTP,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Loss of isoantigens A, B and H in prostate.
March 1973, The American journal of pathology,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Isoantigens A, B, H(O) in nasopharyngeal carcinoma.
January 1983, Cancer,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Epithelial isoantigens A, B and H in oral carcinomas.
May 1985, Ear, nose, & throat journal,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
Isoantigens A, B and H in primary liver malignancies.
July 1981, Pathology,
R Stejskal, and J Mlsna, and P J Delort, and I Davidsohn
H substance - a precursor of A and B tissue isoantigens.
July 1975, Experientia,
Copied contents to your clipboard!