Biomaterial Database

[Experiments with vaccination against infectious epididymitis in rams]. 1978

N Masalski

Two killed vaccines were produced, differing by the adjuvant used--a hydroxide one and an oil one--employing four strains of Brucella ovis. They were applied twice at an interval of 20 days to rams under experimental conditions as well as to rams in filed conditions. On the 45th day following vaccination the experimental rams were challenged with a virulent Brucella ovis strain. To determine the acquired resistance the rams were investigated after the complement-fixation test, hemagglutination reaction, and agar gel immunodiffusion as well as through clinical and bacteriological examination of sampled semen for the presence of bacteria. It was established that rams treated with an oil vaccine built up a solid immunity. The postvaccinal antibodies disappeared after the third month of vaccination. It is suggested to carry out vaccinations with rams of the infected flocks each 6 months. The infected animals can be identified by means of serologic examination three months following vaccination. Vaccination makes it possible to use valuable animals for a longer period, which, though infected are not hazardous in spreading the infection in the flock. A programme is referred to for the curing of flocks by means of vaccination applied to the intact rams and gradual elimination of the infected animals.

UI	MeSH Term	Description	Entries
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007075	Immunoglobulin M	A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin.	Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D008297	Male		Males
D002004	Brucella Vaccine	A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.	Vaccine, Brucella
D004823	Epididymitis	Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.	Epididymitides
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000907	Antibodies, Bacterial	Immunoglobulins produced in a response to BACTERIAL ANTIGENS.	Bacterial Antibodies
D012756	Sheep	Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.	Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D012757	Sheep Diseases	Diseases of domestic and mountain sheep of the genus Ovis.	Ovine Diseases,Disease, Ovine,Disease, Sheep,Diseases, Ovine,Diseases, Sheep,Ovine Disease,Sheep Disease
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor