BIOMAT Database Logo BIOMAT Database Logo

Topical bleomycin-dimethylsulfoxide in AIDS Kaposi's sarcoma. 1994

J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane

UI MeSH Term Description Entries
D008297 Male Males
D001761 Bleomycin A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. BLEO-cell,Blanoxan,Blenoxane,Bleolem,Bleomicina,Bleomycin A(2),Bleomycin A2,Bleomycin B(2),Bleomycin B2,Bleomycin Sulfate,Bleomycins,Bleomycinum Mack,Bléomycine Bellon,BLEO cell,BLEOcell,Bellon, Bléomycine,Mack, Bleomycinum,Sulfate, Bleomycin
D004121 Dimethyl Sulfoxide A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation. DMSO,Dimethyl Sulphoxide,Dimethylsulfoxide,Dimethylsulphinyl,Dimethylsulphoxide,Dimexide,Rheumabene,Rimso,Rimso 100,Rimso-50,Sclerosol,Sulfinylbis(methane),Rimso 50,Rimso50,Sulfoxide, Dimethyl,Sulphoxide, Dimethyl
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163 Acquired Immunodeficiency Syndrome An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency
D000287 Administration, Topical The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example. Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012514 Sarcoma, Kaposi A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. Kaposi Sarcoma,Kaposi's Sarcoma,Multiple Idiopathic Pigmented Hemangiosarcoma,Kaposis Sarcoma,Sarcoma, Kaposi's
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm

Related Publications

J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
Continuous infusion bleomycin in AIDS-related Kaposi's sarcoma.
June 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
AIDS-associated mucocutaneous Kaposi's sarcoma treated with bleomycin.
December 1992, AIDS (London, England),
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
Cutaneous side-effects of bleomycin in AIDS patients with Kaposi's sarcoma.
January 1990, Lancet (London, England),
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
Kaposi's sarcoma in AIDS.
January 1989, Immunology series,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
[Kaposi's sarcoma in AIDS].
October 1985, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
[Kaposi's sarcoma in AIDS].
September 1993, Nihon rinsho. Japanese journal of clinical medicine,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
[Oral Kaposi's sarcoma (AIDS). X-ray findings in oral Kaposi's sarcoma (AIDS)].
January 1989, Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
Combination chemotherapy with doxorubicin, bleomycin, and vindesine for AIDS-related Kaposi's sarcoma.
May 1996, Cancer,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
Treatment of Kaposi's sarcoma with bleomycin.
January 1979, Cutis,
J M Bonnetblanc, and P Weinbreck, and G Lachatre, and C Bedane
AIDS-related Kaposi's sarcoma.
July 1992, International journal of dermatology,
Copied contents to your clipboard!