-transparent.png){kind=logo}
The extracts from rat submandibular glands (SMGs) induced erythroid differentiation of K-562. The activity was non-dialysable and abolished by heat, trypsin or 2-mercaptoethanol. Follistatin, which neutralizes the erythroid differentiation factor (EDF), had no effects on this activity. Analysis by gel chromatography and polyacrylamide gel electrophoresis-isoelectric focussing showed that the characteristics of this substance were different from those of erythropoietin, TGF-beta 1, EDF, stem cell factor and insulin-like growth factor-1. These results suggest the presence of a novel substance in rat SMGs which induces erythroid differentiation of K-562.
Related Publications
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
May 1990,
Biochemical and biophysical research communications,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
January 1991,
Leukemia research,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
January 1993,
Annales pharmaceutiques francaises,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
May 1983,
Cell differentiation,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
June 1984,
Cell differentiation,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
March 1991,
Gematologiia i transfuziologiia,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
February 1988,
Tumori,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
September 1988,
Proceedings of the National Academy of Sciences of the United States of America,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
June 1984,
Bollettino della Societa italiana di biologia sperimentale,
R Sasaki, and
A Masuyama, and
Y Etoh, and
H Yoshida, and
Y Miura, and
H Sasaki
January 1987,
Leukemia research,
