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The existence of familial-hereditary malignant melanoma can be accepted for sure. Its frequency is estimated with 1 to 7% of all malignant melanomas. An autosomal-dominant mode of inheritance with reduced penetrance or a polygenetic mode of inheritance are discussed. Patients with numerous inherited, clinical and histological atypical naevi, the so called BK-moles, are reported to have a high incidence of malignant melanoma. Hereditary malignant melanomas begin early in life, have a high frequency of multiple primary lesions and show the coincidence of other malignant tumors in this families. Men are affected as often as women. Five own families are described and a review of the literature is given.
M Landthaler, and
O Braun-Falco
January 1974,
Radiobiologia, radiotherapia,
M Landthaler, and
O Braun-Falco
December 1977,
Lijecnicki vjesnik,
M Landthaler, and
O Braun-Falco
November 1976,
Langenbecks Archiv fur Chirurgie,
M Landthaler, and
O Braun-Falco
November 1976,
Langenbecks Archiv fur Chirurgie,
M Landthaler, and
O Braun-Falco
December 1979,
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M Landthaler, and
O Braun-Falco
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Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
M Landthaler, and
O Braun-Falco
March 1980,
Contraception, fertilite, sexualite,
M Landthaler, and
O Braun-Falco
March 1978,
MMW, Munchener medizinische Wochenschrift,
M Landthaler, and
O Braun-Falco
April 1979,
Ceskoslovenska dermatologie,
M Landthaler, and
O Braun-Falco
December 1980,
Deutsche medizinische Wochenschrift (1946),
