Non-mutagenicity of thiadiazole-1,3,4 derivatives in Salmonella typhimurium strains. 1995

A Kalski, and E Janik-Spiechowicz
Department of Radioprotection and Toxicology, Military Medical Academy Lodz, Poland.

The Ames mutagenicity assay with Salmonella typhimurium strains (TA97a, TA98, TA100 and TA102) was used to investigate the ability of five dyes (thiadiazole-1,3,4 derivatives) to induce point mutations. The results did not reveal any mutagenic effects of the tested dyes on the S. typhimurium strains. No mutagenic activity was observed in the experimental series with and without exogenous activation.

UI MeSH Term Description Entries
D009152 Mutagenicity Tests Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests. Genetic Toxicity Tests,Genotoxicity Tests,Mutagen Screening,Tests, Genetic Toxicity,Toxicity Tests, Genetic,Genetic Toxicity Test,Genotoxicity Test,Mutagen Screenings,Mutagenicity Test,Screening, Mutagen,Screenings, Mutagen,Test, Genotoxicity,Tests, Genotoxicity,Toxicity Test, Genetic
D012486 Salmonella typhimurium A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER. Salmonella typhimurium LT2
D013830 Thiadiazoles Heterocyclic compounds composed of a five-membered heterocyclic ring which contains one sulfur and two nitrogen atoms. Thiadiazole

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