Wavelength dependence of light-induced phase shifts and period changes in hamsters. 1995

Z Boulos
Institute for Circadian Physiology, Cambridge, MA 02140, USA.

The wavelength dependence of three different circadian responses to light was compared in Syrian hamsters: phase advances and phase delays induced by 15-min light pulses at CT18 (circadian time 18) and CT13, respectively, and changes in free-running period under different levels of constant illumination (LL) intensity. Fluorescent lamps with transmission maxima at 436, 514, and 658 nm were used for delivering blue, green, and red light, respectively. White fluorescent light was also used in the LL portion of the study. The magnitude of each circadian response was plotted as a function of light intensity expressed in photons cm-2 s-1, and intensity-response relationships for the different wavelengths were quantified by fitting the data with a 4-parameter sigmoidal function using a least-squares curve-fitting routine. For each response type, the curves for the different wavelengths were identical but displaced along the horizontal axis [i.e., the functions differed only in the intensity (sigma) required for producing a half-maximal response]. The values of sigma for green and blue light were similar, while that for red light was several times greater. These results indicate that a single class of photoreceptors with peak sensitivity in the blue-green region mediates light-induced phase advances, phase delays, and changes in the period of the hamster circadian pacemaker.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D008647 Mesocricetus A genus in the order Rodentia and family Cricetidae. One species, Mesocricetus auratus or golden hamster is widely used in biomedical research. Hamsters, Golden,Hamsters, Golden Syrian,Hamsters, Syrian,Mesocricetus auratus,Syrian Golden Hamster,Syrian Hamster,Golden Hamster,Golden Hamster, Syrian,Golden Hamsters,Golden Syrian Hamsters,Hamster, Golden,Hamster, Syrian,Hamster, Syrian Golden,Syrian Hamsters
D009043 Motor Activity Body movements of a human or an animal as a behavioral phenomenon. Activities, Motor,Activity, Motor,Motor Activities
D010507 Periodicity The tendency of a phenomenon to recur at regular intervals; in biological systems, the recurrence of certain activities (including hormonal, cellular, neural) may be annual, seasonal, monthly, daily, or more frequently (ultradian). Cyclicity,Rhythmicity,Biological Rhythms,Bioperiodicity,Biorhythms,Biological Rhythm,Bioperiodicities,Biorhythm,Cyclicities,Periodicities,Rhythm, Biological,Rhythmicities,Rhythms, Biological
D002940 Circadian Rhythm The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs or environmental and physiological stimuli. Diurnal Rhythm,Nyctohemeral Rhythm,Twenty-Four Hour Rhythm,Nycthemeral Rhythm,Circadian Rhythms,Diurnal Rhythms,Nycthemeral Rhythms,Nyctohemeral Rhythms,Rhythm, Circadian,Rhythm, Diurnal,Rhythm, Nycthemeral,Rhythm, Nyctohemeral,Rhythm, Twenty-Four Hour,Rhythms, Circadian,Rhythms, Diurnal,Rhythms, Nycthemeral,Rhythms, Nyctohemeral,Rhythms, Twenty-Four Hour,Twenty Four Hour Rhythm,Twenty-Four Hour Rhythms
D003624 Darkness The absence of light. Darknesses
D006224 Cricetinae A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS. Cricetus,Hamsters,Hamster
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
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