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Acute myeloid leukemia with concomitant expression of T-/B-lymphoid antigens and immunogenotypic alterations exhibiting t(7;12)(q32;q24). 1993
K Kawakubo, and
K Ohyashiki, and
J H Ohyashiki, and
Y Kuriyama, and
A Iwabuchi, and
N Kimura, and
K Sugita, and
S Nakazawa, and
K Toyama
First Department of Internal Medicine, Tokyo Medical College, Japan.
We report here a patient with acute myeloid leukemia (AML) expressing both T- and B-lymphoid-associated antigens. The leukemia cells in this case had rearrangements of not only immunoglobulin heavy-chain but also T-cell-receptor beta- and delta-chain genes. Although a relatively large number of AML patients with lymphoid markers have been reported, only about a dozen AML patients expressing both T- and B-lymphoid markers have been reported so far.
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