BIOMAT Database Logo BIOMAT Database Logo

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. 1975

B N Ames, and J Mccann, and E Yamasaki

UI MeSH Term Description Entries
D008297 Male Males
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008861 Microsomes Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) Microsome
D008862 Microsomes, Liver Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough. Liver Microsomes,Liver Microsome,Microsome, Liver
D009153 Mutagens Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D006639 Histidine An essential amino acid that is required for the production of HISTAMINE. Histidine, L-isomer,L-Histidine,Histidine, L isomer,L-isomer Histidine
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

B N Ames, and J Mccann, and E Yamasaki
Salmonella /Mammalian-Microsome Test to Detect Chemical Mutagens.
December 1978, Journal of food protection,
B N Ames, and J Mccann, and E Yamasaki
Protacine. Absence of mutagenicity on Salmonella/mammalian microsome test.
December 1978, Il Farmaco; edizione pratica,
B N Ames, and J Mccann, and E Yamasaki
Mutagenicity of pyrrolizidine alkaloids in the Salmonella/mammalian-microsome test.
November 1979, Mutation research,
B N Ames, and J Mccann, and E Yamasaki
Mutagenicity testing with Salmonella microsome test.
November 1980, Archives of toxicology,
B N Ames, and J Mccann, and E Yamasaki
Mutagenicity test of dyes used in cosmetics with the Salmonella/mammalian-microsome test.
May 1979, Mutation research,
B N Ames, and J Mccann, and E Yamasaki
The Ames test: a look at the Salmonella/mammalian microsome mutagenicity test.
February 1980, Veterinary and human toxicology,
B N Ames, and J Mccann, and E Yamasaki
Mutagenicity of N-nitroso pyridinol carbamate with the Salmonella/mammalian microsome test.
July 1979, Cancer letters,
B N Ames, and J Mccann, and E Yamasaki
Glutathione and glutathione S-transferases in the Salmonella mammalian-microsome mutagenicity test.
May 1980, Mutation research,
B N Ames, and J Mccann, and E Yamasaki
A standardized procedure for quantification of the Ames Salmonella/mammalian-microsome mutagenicity test.
January 1981, Environmental mutagenesis,
B N Ames, and J Mccann, and E Yamasaki
Salmonella/microsome multiple indicator mutagenicity test.
July 1983, Mutation research,
Copied contents to your clipboard!