Comparison of measured and calculated dose distributions in lung after electron beam treatment of the chest wall. 1994

J Seuntjens, and A Van der Plaetsen, and H Thierens, and M Piessens
Department of Biomedical Physics, University of Gent, Belgium.

In this paper a comparison of measured and calculated absorbed dose distributions due to 6 and 8 MeV electron irradiation of a thorax phantom consisting of layers of tissue equivalent materials and infinite cylindrical rib inhomogeneities are presented. Dose measurements, carried out in lung equivalent tissue using thermoluminescent dosimeters for the phantom with and without the rib inhomogeneities, are compared with calculations using a typical two-dimensional (2-D) treatment planning system and EGS4 Monte Carlo calculations. The results show that the used 2-D planning system generally reproduces the dose distribution for the phantom without the cylindrical inhomogeneities. As results from the calculations of ratios of the doses in the phantom with ribs to the doses in the phantom without ribs, the dose perturbations are well reproduced by the EGS4 Monte Carlo calculations, but seriously underestimated by the planning system. The deviations are in the same direction for both energies, but are more pronounced for 6 MeV electrons. The disagreement between the results of the planning system on one hand and the Monte Carlo calculations and experiments on the other hand for the multirib system used is examined further by calculating dose distributions for a phantom containing only one infinite rib. The calculations show that the 2-D treatment planning system generally yields broader and less profound minima in the dose distribution directly beneath the inhomogeneities, with deviations more prominent at lower energies. In addition to the limitation of the central ray approximation, it is suggested that these discrepancies may be due to a too large electron pencil beam spread resulting from the implementation of a range straggling modification function of limited validity at the depths beyond dose maximum for these energies and these tissues.

UI MeSH Term Description Entries
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008961 Models, Structural A representation, generally small in scale, to show the structure, construction, or appearance of something. (From Random House Unabridged Dictionary, 2d ed) Model, Structural,Structural Model,Structural Models
D009010 Monte Carlo Method In statistics, a technique for numerically approximating the solution of a mathematical problem by studying the distribution of some random variable, often generated by a computer. The name alludes to the randomness characteristic of the games of chance played at the gambling casinos in Monte Carlo. (From Random House Unabridged Dictionary, 2d ed, 1993) Method, Monte Carlo
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D011880 Radiotherapy Planning, Computer-Assisted Computer-assisted mathematical calculations of beam angles, intensities of radiation, and duration of irradiation in radiotherapy. Computer-Assisted Radiotherapy Planning,Dosimetry Calculations, Computer-Assisted,Planning, Computer-Assisted Radiotherapy,Calculation, Computer-Assisted Dosimetry,Calculations, Computer-Assisted Dosimetry,Computer Assisted Radiotherapy Planning,Computer-Assisted Dosimetry Calculation,Computer-Assisted Dosimetry Calculations,Dosimetry Calculation, Computer-Assisted,Dosimetry Calculations, Computer Assisted,Planning, Computer Assisted Radiotherapy,Radiotherapy Planning, Computer Assisted
D011882 Radiotherapy, High-Energy Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle. Megavolt Radiotherapy,High-Energy Radiotherapy,Radiotherapy, Megavolt,High Energy Radiotherapy,Radiotherapy, High Energy
D004583 Electrons Stable elementary particles having the smallest known negative charge, present in all elements; also called negatrons. Positively charged electrons are called positrons. The numbers, energies and arrangement of electrons around atomic nuclei determine the chemical identities of elements. Beams of electrons are called CATHODE RAYS. Fast Electrons,Negatrons,Positrons,Electron,Electron, Fast,Electrons, Fast,Fast Electron,Negatron,Positron
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001703 Biophysics The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things. Mechanobiology
D013819 Thermoluminescent Dosimetry The use of a device composed of thermoluminescent material for measuring exposure to IONIZING RADIATION. The thermoluminescent material emits light when heated. The amount of light emitted is proportional to the amount of ionizing radiation to which the material has been exposed. Dosimetries, Thermoluminescent,Dosimetry, Thermoluminescent,Thermoluminescent Dosimetries

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