[Evaluation of various experimental dyslipoproteinemia models in the study of hypolipidemic agents]. 1994

V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva

Models of experimental dyslipoproteinemias have been developed by using non-inbred rats (males and females) and guinea-pigs. Administration of cholesterol (C) with fats and supplementation of 4-hydroxy-6-methyl-2-thiouracil to male rats and that of C in the mixture of fats to guinea-pigs have been demonstrated to lead to the development of atherogenic dyslipoproteinemias. Genfibrozil, cholestyramine and vasosan II, a new pectin-enriched formulation, promoted normalization of the impaired serum lipoprotein spectrum caused by exogenous C administration. Bilateral ovariectomy in female rats induced atherogenic dyslipoproteinemia. The use of the estrogen derivative methyl ether of 6-oxa-D-homo-8-isoestrone normalized lipid and lipoprotein metabolic disturbances.

UI MeSH Term Description Entries
D006951 Hyperlipoproteinemias Conditions with abnormally elevated levels of LIPOPROTEINS in the blood. They may be inherited, acquired, primary, or secondary. Hyperlipoproteinemias are classified according to the pattern of lipoproteins on electrophoresis or ultracentrifugation. Hyperlipoproteinemia
D008297 Male Males
D004195 Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. Animal Disease Model,Animal Disease Models,Disease Model, Animal
D005069 Evaluation Studies as Topic Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D005260 Female Females
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000960 Hypolipidemic Agents Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. Antihyperlipidemic,Antilipemic,Antilipemic Agents,Antilipemic Drug,Hypolipidemic Agent,Hypolipidemic Drug,Antihyperlipemics,Antihyperlipidemics,Antilipemic Drugs,Antilipemics,Hypolipidemic Drugs,Agent, Hypolipidemic,Agents, Antilipemic,Agents, Hypolipidemic,Drug, Antilipemic,Drug, Hypolipidemic,Drugs, Antilipemic,Drugs, Hypolipidemic
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
January 1975, The Journal of surgical research,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
January 1969, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
April 1991, Revista clinica espanola,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
April 1969, Casopis lekaru ceskych,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
January 1997, Acta otorrinolaringologica espanola,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
September 1987, Gigiena truda i professional'nye zabolevaniia,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
October 1976, Seminars in nuclear medicine,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
March 1987, Atherosclerosis,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
January 1975, Child's brain,
V E Ryzhenkov, and A M Chistiakova, and Iu V Frolova, and V T Lozovskiĭ, and I Iu Kameneva, and L E Vasil'eva
October 2006, Archiv der Pharmazie,
Copied contents to your clipboard!