Gluconate zinc in acrodermatitis enteropathica. 1976

F S Hirsh, and B Michel, and W H Strain

Two children with characteristic findings of acrodermatitis enteropathica were found to have low serum zinc levels prior to therapy. Treatment with zinc gluconate in low dosages resulted in an increase in serum zinc levels and clinical improvement. All family members studied had low serum zinc levels. In addition, we noted a change of hair color to red and excessive drooling just prior to exacerbations in these two patients. The hair color returned to normal with remission.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D004103 Iodoquinol One of the halogenated 8-quinolinols widely used as an intestinal antiseptic, especially as an antiamebic agent. It is also used topically in other infections and may cause CNS and eye damage. It is known by very many similar trade names world-wide. Diiodohydroxyquin,Diodoxyquinoline,Diiodohydroxyquinoline,Diiodoquin,Diodoquin,Diquinol,Entero-Diyod,Entodiba,Sebaquin,Yodoxin,Entero Diyod,EnteroDiyod
D005942 Gluconates Derivatives of gluconic acid (the structural formula HOCH2(CHOH)4COOH), including its salts and esters. Copper Gluconate,Gluconate, Copper
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000169 Acrodermatitis Inflammation involving the skin of the extremities, especially the hands and feet. Several forms are known, some idiopathic and some hereditary. The infantile form is called Gianotti-Crosti syndrome. Gianotti-Crosti Syndrome,Infantile Papular Acrodermatitis,Acrodermatitis Papulosa Infantum,Acropapulo-Vesicular Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndrome,Papular Acrodermatitis of Childhood,Papulovesicular Acrolocated Syndrome,Acrodermatitides,Acrodermatitis Papulosa Infantums,Acropapulo Vesicular Syndrome,Acropapulo-Vesicular Syndromes,Childhood Papular Acrodermatitides,Childhood Papular Acrodermatitis,Erythemato Vesiculo Papulous Eruptive Syndrome,Erythemato-Vesiculo-Papulous Eruptive Syndromes,Gianotti Crosti Syndrome,Infantile Papular Acrodermatitides,Papular Acrodermatitides, Infantile,Papular Acrodermatitis, Infantile,Papulovesicular Acrolocated Syndromes,Syndrome, Acropapulo-Vesicular,Syndrome, Erythemato-Vesiculo-Papulous Eruptive,Syndrome, Gianotti-Crosti,Syndromes, Acropapulo-Vesicular,Syndromes, Erythemato-Vesiculo-Papulous Eruptive,Syndromes, Papulovesicular Acrolocated
D015032 Zinc A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.

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