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Based on the cDNA sequence of the human and bovine endothelin converting enzyme (ECE-1) we have developed a novel reverse transcription polymerase chain reaction to investigate the tissue expression of this gene. We were able to specifically detect the gene mRNA starting from very limited amount of tissue in all human as well as bovine tissues examined. Thus, our results confirm a widespread expression of the ECE-1 gene in human tissues, in keeping with the findings in other species, and suggest a major biological role of ECE-1.
Related Publications
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
November 1997,
The Journal of clinical endocrinology and metabolism,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
April 1999,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
January 1998,
Journal of cardiovascular pharmacology,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
May 1998,
Clinical and experimental hypertension (New York, N.Y. : 1993),
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
March 2008,
Journal of clinical biochemistry and nutrition,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
February 1995,
Biochemical and biophysical research communications,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
June 2006,
Experimental biology and medicine (Maywood, N.J.),
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
August 2002,
Clinical science (London, England : 1979),
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
January 2004,
Clinical endocrinology,
G P Rossi, and
G Albertin, and
E Franchin, and
A Sacchetto, and
M Cesari, and
G Palù, and
A C Pessina
December 1997,
Hypertension (Dallas, Tex. : 1979),
