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The study analyses the performance of 22 mild Alzheimer's disease (AD) patients on the Release from Proactive Interference (RPI) paradigm with the aim to investigate the relationship of RPI with frontal function. Twenty-one normal elderly subjects, age and education matched, constituted the control group. Patients with AD were found to recall less words on each trial of the RPI than did the controls. The analysis of Proactive Interference (PI) and Release from PI, in AD patients, by using Anova (trial x group), showed a significant effect of trial and group but not a group by trial interaction. These results indicate a similarity between the performance of AD patients and normal controls on the Release from Proactive Interference paradigm. Despite the similar pattern of performance, AD patients were significantly inferior to normal controls with regard to global performance level. The AD patients' scores on "frontal lobe" tests were correlated with an index of RPI (shift condition index). The only significant result was with the number of categories on the Wisconsin Card Sorting Test, suggesting a weak correlation between RPI and "frontal lobe" function.
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
December 1988,
Journal of clinical and experimental neuropsychology,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
January 1991,
Neuropsychologia,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
September 2017,
Learning & behavior,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
October 1989,
Journal of experimental psychology. Animal behavior processes,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
January 2021,
Neuroscience and biobehavioral reviews,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
September 1992,
Journal of clinical and experimental neuropsychology,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
March 1977,
Journal of motor behavior,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
September 2014,
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
July 1976,
American journal of mental deficiency,
G Binetti, and
E Magni, and
A Padovani, and
S F Cappa, and
A Bianchetti, and
M Trabucchi
December 1981,
The Journal of genetic psychology,
