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This is the first study in this country of sera from patients with infectious mononucleosis and other infectious diseases (control group) for determination of complement-fixing antibody to the soluble (S) antigen and of fluorescent antibody to the virus capsid antigen (VCA) of Epstein-Barr virus. It was established that the CFT and the immunofluorescence test could be used for diagnosis of infectious mononucleosis only on a limited scale because of the lack of complement-fixing antibody in patients early in the convalescent period and because of the presence of complement-fixing and fluorescent antibody in a high per cent of patients of the control group.
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