BIOMAT Database Logo BIOMAT Database Logo

Effect of cholinergic stimulation of the amygdaloid complex on water and salt intake. 1994

W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
Departamento de Ciências Fisiológicas, Faculdade de Odontologia, Universidade Estadual Paulista, Araraquara, SP, Brasil.

The effect of carbachol (80 nmol/microliters) injection into the amygdaloid nuclear complex (AMG) on sodium appetite and water intake was studied in male Holtzman rats weighing 240-270 g. Twenty-five satiated rats and 38 water-deprived rats were used in the experiment on water intake. In the experiment on sodium intake, 19 rats were injected with atropine+carbachol and 9 rats with hexamethonium+carbachol. After carbachol injection into the AMG, water intake decreased in rats submitted to 30 h of water deprivation (10.28 +/- 1.04 ml/120 min vs 0.69 +/- 0.22 ml/120 min). The decrease in water intake was blocked by prior local injection of atropine (20 nmol/l microliters) (11.66 +/- 1.46 ml/120 min vs 0.69 +/- 0.22 ml/120 min), but not of hexamethonium (30 nmol/1 microliters), into the AMG. In water-deprived animals, carbachol injection into the AMG caused a decrease in sodium chloride intake (6.16 +/- 1.82 ml/h vs 0.88 +/- 0.54 ml/h) which was blocked by previous injection of hexamethonium but not of atropine. These results suggest that the cholinergic system of the AMG plays a role in the control of water and salt intake.

UI MeSH Term Description Entries
D007267 Injections Introduction of substances into the body using a needle and syringe. Injectables,Injectable,Injection
D008297 Male Males
D010276 Parasympatholytics Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. Antispasmodic,Antispasmodic Agent,Antispasmodic Drug,Antispasmodics,Parasympathetic-Blocking Agent,Parasympathetic-Blocking Agents,Parasympatholytic,Parasympatholytic Agent,Parasympatholytic Drug,Spasmolytic,Spasmolytics,Antispasmodic Agents,Antispasmodic Drugs,Antispasmodic Effect,Antispasmodic Effects,Parasympatholytic Agents,Parasympatholytic Drugs,Parasympatholytic Effect,Parasympatholytic Effects,Agent, Antispasmodic,Agent, Parasympathetic-Blocking,Agent, Parasympatholytic,Agents, Antispasmodic,Agents, Parasympathetic-Blocking,Agents, Parasympatholytic,Drug, Antispasmodic,Drug, Parasympatholytic,Drugs, Antispasmodic,Drugs, Parasympatholytic,Effect, Antispasmodic,Effect, Parasympatholytic,Effects, Antispasmodic,Effects, Parasympatholytic,Parasympathetic Blocking Agent,Parasympathetic Blocking Agents
D002217 Carbachol A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS. Carbamylcholine,Carbacholine,Carbamann,Carbamoylcholine,Carbastat,Carbocholine,Carboptic,Doryl,Isopto Carbachol,Jestryl,Miostat,Carbachol, Isopto
D004326 Drinking The consumption of liquids. Water Consumption,Water Intake,Drinkings
D006584 Hexamethonium Compounds Compounds containing the hexamethylenebis(trimethylammonium) cation. Members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents. Compounds, Hexamethonium
D000679 Amygdala Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system. Amygdaloid Body,Amygdaloid Nuclear Complex,Amygdaloid Nucleus,Archistriatum,Corpus Amygdaloideum,Intercalated Amygdaloid Nuclei,Massa Intercalata,Nucleus Amygdalae,Amygdalae, Nucleus,Amygdaloid Bodies,Amygdaloid Nuclear Complices,Amygdaloid Nuclei, Intercalated,Amygdaloid Nucleus, Intercalated,Amygdaloideum, Corpus,Amygdaloideums, Corpus,Archistriatums,Complex, Amygdaloid Nuclear,Complices, Amygdaloid Nuclear,Corpus Amygdaloideums,Intercalata, Massa,Intercalatas, Massa,Intercalated Amygdaloid Nucleus,Massa Intercalatas,Nuclear Complex, Amygdaloid,Nuclear Complices, Amygdaloid,Nuclei, Intercalated Amygdaloid,Nucleus, Amygdaloid,Nucleus, Intercalated Amygdaloid
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001285 Atropine An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine. AtroPen,Atropin Augenöl,Atropine Sulfate,Atropine Sulfate Anhydrous,Atropinol,Anhydrous, Atropine Sulfate,Augenöl, Atropin,Sulfate Anhydrous, Atropine,Sulfate, Atropine
D014868 Water Deprivation The withholding of water in a structured experimental situation. Deprivation, Water,Deprivations, Water,Water Deprivations

Related Publications

W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
Effect of cholinergic and adrenergic stimulation of the subfornical organ on water intake.
February 1984, Pharmacology, biochemistry, and behavior,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
The effect of amygdaloid stimulation on daily food intake in cats.
January 1968, Acta biologiae experimentalis,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
Long-lasting effects of cholinergic stimulation of the amygdaloid complex in the rat.
August 1972, Journal of comparative and physiological psychology,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
[Effect of electric stimulation of the amygdaloid complex on hemodynamic shifts].
January 1973, Fiziolohichnyi zhurnal,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
[Cholinergic aspects of the peripheral regulation of water and salt solution intake].
April 1984, Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
The effect of water and salt intake on prickly heat.
August 1949, Lancet (London, England),
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
[Effect of stimulation of amygdaloid nuclear complex on blood coagulating indices].
July 1969, Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
[Effect of high-frequency stimulation of the amygdaloid complex on memory in rats].
January 1971, Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
[Effect of stimulation of the amygdaloid body on water-excretory function of the kidneys].
April 1982, Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
W A Saad, and R M Bengtson, and J V Menani, and L A Camargo, and A Renzi, and J E Silveira, and W A Saad
Water and salt intake induced by hypothalamic implants of cholinergic and adrenergic agents.
June 1969, The American journal of physiology,
Copied contents to your clipboard!