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The effect of oil-attached BCG cell-wall skeleton on the induction of pleural fibrosarcomas by 3-methylcholanthrene in mice was examined. The pleural fibrosarcomas were induced by a substernal injection of 3-methylcholanthrene into the thoracic cavity of ddO mice. One week after the injection of 3-methylcholanthrene, 100 mug of oil-attached BCG cell-wall skeleton was injected subcutaneously every week for 10 weeks. In the observation period of 130 days, the incidence of pleural fibrosarcoma was 67% in the control mice and 39% in the mice treated with BCG cell-wall skeleton. The latent period of tumor induction was prolonged in the mice treated with BCG cell-wall skeleton.
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
August 1975,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
April 1979,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
August 1975,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
February 1979,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
December 1975,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
October 1976,
Gan,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
December 1984,
Journal of biological response modifiers,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
October 1977,
Kekkaku : [Tuberculosis],
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
April 1979,
Cancer,
T Yoshimoto, and
I Azuma, and
M Sakatani, and
H Nishikawa, and
T Ogura
May 1978,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
