Biomaterial Database

[The relationship of amniotic fluid volume and fetal renal function to fetal distress in intrauterine growth retardation]. 1994

T Miyamura

Department of Obstetrics and Gynecology, Nagasaki University School of Medicine.

The Hourly fetal urine production rate (HFUPR) was measured by ultrasound to evaluate the relationship between qualitative amniotic fluid volume (vertical depth of amniotic cavity) and fetal renal function. A positive correlation was found between HFUPR and neonatal birth weight (r = 0.625, p < 0.01), and between HFUPR and the vertical depth of the amniotic cavity (r = 0.615, p < 0.01). In three cases of IUGR complicated by fetal distress, the cyclicity of micturition disappeared and the vertical depth of the amniotic cavity was less than 30mm. The values for urinary beta 2-microglobulin were significantly higher in three neonates with fetal distress (15.00 +/- 1.00mg/L) than in healthy neonates (1.51 +/- 1.48mg/L) (p < 0.01). The mean value for vertical depth of the amniotic cavity in normal pregnancies was stable during pregnancy (mean +/- 2SD; 30-80mm). Thus patients with an amniotic cavity vertical depth less than 30mm were classified as decreased. In the IUGR group, the vertical depth of the amniotic cavity was normal in 81 patients, 14 of whom gave birth to a fetus with fetal distress. In contrast, the vertical depth of the amniotic cavity was decreased in 34 patients, 26 of whom gave birth to a fetus with fetal distress. The difference was significant (76.5% vs 17.3%, p < 0.01). The incidence of fetal distress was significantly related to the vertical depth of the amniotic cavity in the IUGR group.

UI	MeSH Term	Description	Entries
D007668	Kidney	Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.	Kidneys
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D005260	Female		Females
D005316	Fetal Distress	A nonreassuring fetal status (NRFS) indicating that the FETUS is compromised (American College of Obstetricians and Gynecologists 1988). It can be identified by sub-optimal values in FETAL HEART RATE; oxygenation of FETAL BLOOD; and other parameters.	Nonreassuring Fetal Status,Fetal Status, Nonreassuring
D005317	Fetal Growth Retardation	Failure of a FETUS to attain expected GROWTH.	Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000653	Amniotic Fluid	A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).	Amniotic Fluid Index,Amniotic Fluid Indices,Amniotic Fluids,Fluid Index, Amniotic,Fluid Indices, Amniotic,Fluid, Amniotic,Fluids, Amniotic,Index, Amniotic Fluid,Indices, Amniotic Fluid
D016216	Ultrasonography, Prenatal	The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.	Fetal Ultrasonography,Prenatal Diagnosis, Ultrasonic,Ultrasonography, Fetal,Diagnosis, Prenatal Ultrasonic,Diagnosis, Ultrasonic Prenatal,Prenatal Ultrasonic Diagnosis,Prenatal Ultrasonography,Ultrasonic Diagnosis, Prenatal,Ultrasonic Prenatal Diagnosis,Diagnoses, Prenatal Ultrasonic,Diagnoses, Ultrasonic Prenatal,Prenatal Diagnoses, Ultrasonic,Prenatal Ultrasonic Diagnoses,Ultrasonic Diagnoses, Prenatal,Ultrasonic Prenatal Diagnoses