Biomaterial Database

Inhibition of pentagastrin-stimulated secretion of acid and pepsin by trimipramine in man. 1976

A Berstad, and M Roland, and J Myren

UI	MeSH Term	Description	Entries
D010418	Pentagastrin	A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.	Acignost,Gastrin Pentapeptide,Peptavlon,Pentapeptide, Gastrin
D010434	Pepsin A	Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.	Pepsin,Pepsin 1,Pepsin 3
D003984	Dibenzazepines	Compounds with two BENZENE rings fused to AZEPINES.
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005750	Gastric Juice	The liquid secretion of the stomach mucosa consisting of hydrochloric acid (GASTRIC ACID); PEPSINOGENS; INTRINSIC FACTOR; GASTRIN; MUCUS; and the bicarbonate ion (BICARBONATES). (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p651)	Gastric Juices,Juice, Gastric,Juices, Gastric
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012636	Secretory Rate	The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.	Rate, Secretory,Rates, Secretory,Secretory Rates
D014299	Trimipramine	Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.	Trimeprimine,10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine,Apo-Trimip,Eldoral,Herphonal,Novo-Tripramine,Nu-Trimipramine,Rhotrimine,Stangyl,Surmontil,Surmontil Maleate,Trimidura,Trimineurin,Trimineurin Maleate,Trimipramin AZU,Trimipramin Beta,Trimipramin Stada,Trimipramin-Neurazpharm,Trimipramine Maleate,Trimipramine Maleate (1:1),Trimipramine Maleate (1:1), (+)-Isomer,Trimipramine Maleate (1:1), (+-)-Isomer,Trimipramine Maleate (1:1), (-)-Isomer,Trimipramine Mesylate,Trimipramine Monohydrochloride,Trimipramine, (+-)-Isomer,Trimipramine, (-)-Isomer,Apo Trimip,ApoTrimip,Beta, Trimipramin,Novo Tripramine,NovoTripramine,Nu Trimipramine,NuTrimipramine,Trimipramin Neurazpharm,TrimipraminNeurazpharm