-transparent.png){kind=logo}
The effect of filtration on the quality of platelet concentrates (PC) during storage was investigated. Two leukocyte depletion filters (Pall PL50HF and Sepacell PL-10A) were applied to filter PC made from a pool of 4 buffy coats. For each experiment 3 PC were pooled and divided into 3 identical PC to eliminate differences between the PC. Two PC were filtered, and the third PC served as an unfiltered control. A total of 12 experiments was performed. Before filtration, volumes of the PC were 263 +/- 11.7 ml (mean +/- SD). Platelet and leukocyte counts per PC were 241 +/- 25.9 x 10(9) and 7.2 +/- 1.8 x 10(6), respectively. After filtration leukocyte counts did not exceed 5 x 10(4) in any of the PC. In the PC filtered with the Pall PL50HF the mean platelet loss was approximately 14% and with the Sepacell PL-10A, 17%. During a 9-day storage period the pH, PO2, PCO2, bicarbonate, lactate and glucose concentration and LDH release as well as the morphology, examined by the swirling effect and microscopically, were not significantly different in filtered and unfiltered units. Filtration through the 2 investigated leukocyte depletion filters for PC did not adversely affect in vitro viability of the platelets during storage.
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 1992,
Vox sanguinis,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 2022,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 1986,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
June 1991,
Infusionstherapie (Basel, Switzerland),
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 1981,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
February 1993,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
May 1996,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 1982,
Transfusion,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
January 1989,
Vox sanguinis,
A M Joustra-Dijkhuis, and
M N Boomgaard, and
R N Pietersz, and
I Steneker, and
D de Korte, and
J A Loos, and
H W Reesink
February 1993,
Transfusion,
