Continuous positive airway pressure breathing increases cerebral blood flow velocity in humans. 1994

H P Haring, and C Hörmann, and S Schalow, and A Benzer
Department of Neurology, University Hospital, Innsbruck, Austria.

The effect of a continuous positive airway pressure (CPAP) of 12 cm H2O on mean middle cerebral artery flow velocity (CBFV) was studied in nine human volunteers by means of transcranial Doppler sonography (TCD). During CPAP breathing, CBFV increased (45 +/- 9 vs 59 +/- 11 cm/s; P < 0.001; mean +/- SD), and pulsatility index (PI) decreased (0.87 +/- 0.1 vs 0.74 +/- 0.2; P < 0.05), indicating an increase in cerebral blood flow due to cerebral vasodilation. This phenomenon should be taken into account when CPAP is applied to patients with intracranial disease or when assessing CBFV patterns of patients during CPAP respiration.

UI MeSH Term Description Entries
D008297 Male Males
D011175 Positive-Pressure Respiration A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange. Positive End-Expiratory Pressure,Positive-Pressure Ventilation,End-Expiratory Pressure, Positive,End-Expiratory Pressures, Positive,Positive End Expiratory Pressure,Positive End-Expiratory Pressures,Positive Pressure Respiration,Positive Pressure Ventilation,Positive-Pressure Respirations,Positive-Pressure Ventilations,Pressure, Positive End-Expiratory,Pressures, Positive End-Expiratory,Respiration, Positive-Pressure,Respirations, Positive-Pressure,Ventilation, Positive-Pressure,Ventilations, Positive-Pressure
D001783 Blood Flow Velocity A value equal to the total volume flow divided by the cross-sectional area of the vascular bed. Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D002560 Cerebrovascular Circulation The circulation of blood through the BLOOD VESSELS of the BRAIN. Brain Blood Flow,Regional Cerebral Blood Flow,Cerebral Blood Flow,Cerebral Circulation,Cerebral Perfusion Pressure,Circulation, Cerebrovascular,Blood Flow, Brain,Blood Flow, Cerebral,Brain Blood Flows,Cerebral Blood Flows,Cerebral Circulations,Cerebral Perfusion Pressures,Circulation, Cerebral,Flow, Brain Blood,Flow, Cerebral Blood,Perfusion Pressure, Cerebral,Pressure, Cerebral Perfusion
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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